Micronutrients
Vitamins and minerals — small amounts, massive impact.
📖 The Story: The Modern Micronutrient Paradox
Meet Emma—she tracks her macros religiously, eats 2,000 calories a day of "clean" food, and still feels terrible.
She's tired despite sleeping eight hours. Her brain feels foggy by 2pm. She catches every cold that goes around. Her nails are brittle and her hair is thinning. Her doctor says her basic bloodwork is "normal."
What Emma doesn't realize: she's hitting her calorie and protein targets while starving her body of the micronutrients that make everything work.
Her vitamin D is 18 ng/mL (should be 40-60). Her magnesium is depleted from stress and coffee. Her B12 is borderline because she rarely eats meat. Her iron is low-normal but she's symptomatic. None of this shows up on a standard metabolic panel.
This is the modern micronutrient paradox: We have more food than ever, yet widespread subclinical deficiencies.
Why? Because calories aren't everything:
- Processed foods provide energy but strip out vitamins and minerals
- Industrial farming has depleted soil minerals by 30-76% since 1950
- Indoor lifestyles mean 40%+ of adults are vitamin D insufficient
- Chronic stress burns through magnesium and B vitamins faster than we replenish
- Medications (PPIs, metformin, statins) deplete specific nutrients
In 1912, the discovery that scurvy was caused by vitamin C absence revolutionized medicine. Today's challenge is subtler: not dramatic deficiency diseases, but the quiet impairment of millions of biochemical reactions.
The result? You don't feel "sick." You feel "off"—tired, foggy, anxious, prone to illness, not recovering well, aging faster than you should. And because standard tests don't catch it, you're told nothing's wrong.
The solution isn't complicated, but it requires understanding what your body actually needs beyond protein, carbs, and fats.
🚶 The Journey: How Micronutrients Move Through Your Body
Understanding how vitamins and minerals travel from your plate to your cells helps explain why certain combinations work better together — and why deficiency symptoms can be so varied.
The Path of Fat-Soluble Vitamins (A, D, E, K)
Timeline: Takes 3-6 hours to absorb, but builds up reserves over weeks to months.
Why fat matters: Without dietary fat in the meal, absorption drops by 50-70%. This is why taking vitamin D with a fat-free breakfast is essentially wasted.
Storage capacity:
- Vitamin A: Liver stores last 1-2 years
- Vitamin D: Fat tissue; depletes over months
- Vitamin E: Fat tissue and liver
- Vitamin K: Limited storage (days to weeks)
The Path of Water-Soluble Vitamins (B-Complex, C)
Timeline: Absorbed within 1-3 hours; excess eliminated same day.
Exception — B12: Requires intrinsic factor from stomach for absorption, and liver stores 2-5 years' worth.
Why daily intake matters: With minimal storage, your body needs regular replenishment. Miss a few days of vitamin C, and tissue levels start dropping.
The Path of Minerals
Macrominerals (Calcium, Magnesium):
Calcium's journey:
- Requires vitamin D for absorption
- Requires vitamin K2 to reach bones (not arteries)
- Competes with magnesium, iron, zinc
- Only 20-40% absorbed; rest excreted
Magnesium's journey:
- Absorbed throughout small intestine
- 60% stored in bones; 40% in muscles and tissues
- Serum levels tell you almost nothing (only 1% is in blood)
- Depleted by stress, alcohol, processed foods
Trace Minerals (Iron, Zinc, Selenium):
Iron's path:
- Heme iron (meat): 15-35% absorbed directly
- Non-heme iron (plants): 2-20% absorbed (boosted 3x by vitamin C)
- Stored in ferritin; no excretion mechanism
- Takes 3-6 months to rebuild depleted stores
Zinc's path:
- Competes with copper and iron
- Phytates (grains, legumes) block absorption by 50%
- Lost in sweat during exercise
- Absorption: 20-40% of intake
What Happens When You're Deficient
Acute deficiency (weeks to months):
| Timeline | What Depletes | Symptoms Begin |
|---|---|---|
| Days-weeks | Water-soluble vitamins (C, B-complex except B12) | Fatigue, mood changes |
| Weeks-months | Magnesium, iron (from stores) | Muscle cramps, weakness, fatigue |
| Months | Vitamin D (in winter), B12 (in vegans) | Low mood, immune issues, numbness |
| Years | Fat-soluble vitamins (if zero intake) | Vision, bone, bleeding problems |
The cascade effect:
One deficiency often leads to another because nutrients work together:
- Low vitamin D → Poor calcium absorption → Weak bones
- Low magnesium → Vitamin D can't activate → Both become deficient
- Low vitamin C → Poor iron absorption → Anemia despite adequate iron intake
- Low B12 → Elevated homocysteine → Folate can't work properly
👀 Signs & Signals: What Your Body Is Telling You
Your body sends remarkably specific signals when micronutrients are running low. While these symptoms overlap and aren't diagnostic on their own, patterns can point you toward what to test.
| Body Signal | Possible Deficiency | What's Happening | Next Step |
|---|---|---|---|
| Fatigue (despite adequate sleep) | Iron, B12, Vitamin D, Magnesium | Energy production impaired at cellular level | Test: Ferritin, B12, 25-OH-D |
| Muscle cramps or twitches | Magnesium, Potassium, Calcium | Electrolyte imbalance affecting nerve-muscle signaling | Consider: Magnesium 200-400 mg |
| Frequent infections | Vitamin D, Zinc, Vitamin C, Vitamin A | Immune cells not functioning optimally | Test: Vitamin D; consider zinc |
| Poor wound healing | Zinc, Vitamin C, Protein | Collagen synthesis and tissue repair impaired | Increase protein + vitamin C + zinc |
| Numbness or tingling (hands/feet) | B12, B6, Magnesium | Nerve damage or dysfunction | Test: B12 + MMA; urgent if progressive |
| Hair loss or thinning | Iron, Zinc, Biotin, Vitamin D | Follicle cells dividing slowly; inflammatory processes | Test: Ferritin (should be 50-70 for hair) |
| Brittle nails or ridges | Iron, Zinc, Biotin, Protein | Keratin production affected | Test: Ferritin; increase protein |
| Dry, scaly skin | Vitamin A, Omega-3s, Zinc | Skin cell turnover and barrier function impaired | Add omega-3s; check zinc |
| Night blindness or slow dark adaptation | Vitamin A | Rhodopsin (visual pigment) synthesis affected | Increase vitamin A-rich foods |
| Easy bruising | Vitamin C, Vitamin K | Collagen fragility (C) or clotting factors (K) | Increase vegetables; check vitamin K |
| Bleeding gums | Vitamin C | Collagen breakdown in gum tissue | Increase vitamin C intake |
| Bone pain or fractures | Vitamin D, Calcium, K2, Magnesium | Bone mineralization compromised | Test: Vitamin D + DEXA if concerning |
| Restless leg syndrome | Iron, Magnesium | Dopamine dysfunction (iron) or nerve excitability (Mg) | Test: Ferritin; try magnesium |
| Depression or low mood | Vitamin D, B vitamins, Omega-3, Magnesium | Neurotransmitter synthesis affected | Test: D, B12; add omega-3 + Mg |
| Mouth ulcers or cracked corners | B12, Iron, Folate, B2 (Riboflavin) | Cell turnover in mucous membranes slowed | Consider B-complex |
| Brain fog or poor concentration | B12, Iron, Vitamin D, Magnesium | Oxygen delivery, neurotransmitters, or energy affected | Test: Ferritin, B12, D |
| Irregular heartbeat | Magnesium, Potassium | Electrolyte imbalance affecting cardiac electrical activity | Medical evaluation + test Mg |
Pattern Recognition: When Multiple Symptoms Point to One Deficiency
Classic Iron Deficiency Pattern:
- Fatigue (earliest sign)
- Pale skin and pale inner eyelids
- Cold hands and feet
- Shortness of breath with exertion
- Restless legs at night
- Craving ice or other non-food items (pica)
- Brittle nails or hair loss
Classic B12 Deficiency Pattern:
- Fatigue and weakness
- Numbness or tingling (starts in hands/feet)
- Balance problems
- Memory issues or "brain fog"
- Smooth, swollen tongue
- Mood changes or depression
Classic Vitamin D Deficiency Pattern:
- Persistent low mood (especially winter)
- Frequent colds or infections
- Muscle weakness or aches
- Bone pain
- Slow wound healing
- Fatigue
Classic Magnesium Deficiency Pattern:
- Muscle cramps or spasms (especially at night)
- Eyelid twitches
- Trouble sleeping or staying asleep
- Anxiety or feeling "wired"
- Headaches or migraines
- Irregular heartbeat or palpitations
The "Hidden" Deficiencies
Some deficiencies don't show obvious symptoms until they're severe:
| Nutrient | Why It Hides | What Eventually Happens |
|---|---|---|
| Vitamin K | Adequate clotting until severe | Bruising, bleeding; poor bone health long-term |
| Selenium | Body prioritizes vital organs | Thyroid dysfunction, immune weakness, fertility issues |
| Copper | Symptoms are non-specific | Anemia that doesn't respond to iron, neutropenia |
| Choline | Body makes some from other nutrients | Fatty liver, memory issues (takes years) |
🧠 The Science: Understanding Micronutrients
What Are Micronutrients?
| Category | What They Are | Storage | Key Difference |
|---|---|---|---|
| Vitamins | Organic compounds (contain carbon) | Varies by type | Made by living things |
| Minerals | Inorganic elements | Body tissues | Come from soil/water |
Fat-Soluble vs. Water-Soluble Vitamins
- Fat-Soluble (A, D, E, K)
- Water-Soluble (B, C)
Characteristics:
- Dissolve in fat, not water
- Stored in liver and fat tissue
- Don't need daily intake (body has reserves)
- Can accumulate to toxic levels if over-supplemented
Absorption:
- Require dietary fat for absorption
- Absorbed with fat in small intestine
- Travel via lymphatic system
Deficiency timeline: Takes months to years to develop (except K)
Characteristics:
- Dissolve in water
- Not stored significantly (except B12 in liver)
- Need regular intake
- Excess excreted in urine (toxicity rare)
Absorption:
- Absorbed directly into bloodstream
- Travel freely in blood
Deficiency timeline: Can develop in weeks to months
Macrominerals vs. Trace Minerals
| Category | Amount Needed | Examples | Notes |
|---|---|---|---|
| Macrominerals | >100 mg/day | Calcium, Magnesium, Potassium, Sodium, Phosphorus, Chloride, Sulfur | Make up >0.01% of body weight |
| Trace Minerals | Under 100 mg/day | Iron, Zinc, Copper, Selenium, Iodine, Manganese, Chromium, etc. | Needed in tiny amounts but still essential |
Why Deficiencies Are So Common
Prevalence of common deficiencies:
| Nutrient | % Deficient/Low | At-Risk Groups |
|---|---|---|
| Vitamin D | 40%+ | Indoor workers, dark skin, elderly, northern latitudes |
| Magnesium | 50%+ | Most adults; depleted by stress, alcohol, processed food |
| Potassium | 98% below AI | Almost everyone (processed food is low in K) |
| Vitamin B12 | 10-15% | Vegans, elderly (>50), gut issues, on PPIs |
| Iron | 10% (higher in women) | Menstruating women, vegetarians, endurance athletes |
| Zinc | 10-15% | Vegetarians, elderly, gut issues |
| Omega-3 | 70%+ | Those not eating fatty fish |
🎯 Nutrient Interactions: Synergies & Antagonisms
Understanding how nutrients interact is crucial — taking one nutrient can enhance or block another.
Synergistic Interactions (Beneficial)
| Combination | Effect | Practical Tip |
|---|---|---|
| Vitamin D + Calcium | D increases calcium absorption | Take together |
| Vitamin D + K2 | K2 directs calcium to bones, not arteries | Supplement together |
| Vitamin C + Iron | C converts iron to absorbable form, 2-3x increase | Eat citrus with iron-rich foods |
| Vitamin B6 + Magnesium | B6 may improve Mg absorption | Often combined in supplements |
| Fat + Fat-soluble vitamins | Fat required for A, D, E, K absorption | Take with meals containing fat |
| MFP factor + Non-heme iron | Meat/fish/poultry increases plant iron absorption 2-3x | Combine at meals |
Antagonistic Interactions (Competing)
| Combination | Effect | How to Manage |
|---|---|---|
| Calcium + Iron | High calcium inhibits iron absorption | Separate by 2+ hours |
| Calcium + Magnesium | Compete at high doses (>2:1 ratio) | Maintain ~2:1 Ca:Mg ratio |
| Zinc + Copper | High zinc depletes copper | Supplement at 8-15:1 Zn:Cu ratio |
| High-dose Vitamin A + Vitamin D | A may decrease D absorption by 30% | Don't mega-dose A |
| Iron + Zinc | Compete for absorption | Separate if supplementing |
Absorption Blockers (Anti-nutrients)
| Compound | Found In | Blocks | How to Reduce |
|---|---|---|---|
| Phytates | Grains, legumes, nuts | Iron, zinc, calcium | Soak, sprout, or ferment |
| Oxalates | Spinach, rhubarb, beets | Calcium, iron | Cook to reduce; vary greens |
| Tannins | Tea, coffee, wine | Iron | Don't drink with iron-rich meals |
| Calcium | Dairy, supplements | Iron | Separate from iron sources |
Practical takeaway: Nutrient interactions explain why whole foods often work better than isolated supplements — nature packages nutrients together in balanced, synergistic combinations. When supplementing, timing and combinations matter.
🎯 Making It Work: Practical Micronutrient Strategy
The Food-First Strategy
Before reaching for supplements, optimize food intake with nutrient-dense whole foods:
| Food | Key Nutrients | Why It's Powerful |
|---|---|---|
| Liver | A, B12, iron, copper, folate, choline | Nature's multivitamin |
| Oysters | Zinc, B12, copper, selenium | Highest zinc food |
| Fatty fish | D, B12, selenium, omega-3s | Multiple benefits |
| Eggs | B vitamins, choline, D, selenium | Complete nutrition |
| Leafy greens | K, folate, magnesium, potassium | Mineral-rich |
| Nuts & seeds | Magnesium, zinc, E, selenium | Mineral powerhouses |
| Colorful vegetables | Various vitamins, antioxidants | Phytonutrient diversity |
When to Consider Supplementation
Almost everyone may benefit from:
- Vitamin D — If not getting regular sun exposure (most people)
- Omega-3s — If not eating fatty fish 2x/week
- Magnesium — If diet is low in nuts/seeds/greens or symptomatic
Specific populations:
| Group | Consider Supplementing |
|---|---|
| Vegans | B12 (mandatory), D, omega-3 (algae), iron, zinc |
| Elderly (50+) | B12, D, calcium |
| Pregnant women | Folate, iron, D, choline, iodine |
| Athletes | Magnesium, iron (if deficient), D, zinc |
| Those on PPIs | B12, magnesium, calcium |
Testing: When and What
Key markers to consider testing:
| Test | Target Range | When to Test |
|---|---|---|
| 25-hydroxyvitamin D | 40-60 ng/mL | Annually, or if symptomatic |
| Serum B12 | >400 pg/mL | If vegan, elderly, or symptomatic |
| Ferritin | 30-100 ng/mL (varies) | If fatigue, women, athletes |
| RBC Magnesium | 5.0-6.5 mg/dL | If symptomatic (serum is unreliable) |
| Zinc (plasma) | 70-120 mcg/dL | If deficiency suspected |
Test, don't guess — especially for vitamin D, B12, and iron. Symptoms of deficiency overlap significantly, and over-supplementing some nutrients (iron, A) can be harmful.
📸 What It Looks Like: A Micronutrient-Rich Day
Example Day: Covering All Bases
This day hits the key micronutrients most people miss, using whole foods:
Breakfast:
- 2 eggs scrambled with spinach and bell peppers
- 1/2 avocado on whole grain toast
- Orange
What you're getting: Choline, B12, folate, vitamins A, C, E, K, magnesium, potassium, iron
Lunch:
- Salmon salad with mixed greens, pumpkin seeds, chickpeas
- Greek yogurt with berries
What you're getting: Vitamin D, B12, omega-3s, zinc, magnesium, calcium, selenium, vitamin C, antioxidants
Snack:
- Handful of almonds
- Dark chocolate square
What you're getting: Magnesium, vitamin E, zinc, antioxidants
Dinner:
- Beef stir-fry with broccoli, sweet potato, and white beans
- Side of sauerkraut
What you're getting: Iron, zinc, B vitamins, vitamin C, potassium, K2 from fermented food
Daily totals hit well: A, C, D (partial—supplement likely still needed), E, K, B vitamins, magnesium, potassium, iron, zinc, calcium (partial), selenium, omega-3s
What's likely still needed:
- Vitamin D3: Unless you got significant sun, supplement 2,000-4,000 IU
- Possibly magnesium: Food may not fully cover needs—consider 200 mg glycinate at bedtime
The "Micronutrient Superstar" Foods
If you could only add a few foods, these cover the most ground:
| Food | Frequency | What You're Getting |
|---|---|---|
| Eggs | Daily (2) | Choline, B12, D, A, selenium |
| Fatty fish | 2x/week | D, B12, omega-3s, selenium |
| Leafy greens | Daily | K, folate, magnesium, potassium |
| Pumpkin seeds | Daily (1 oz) | Magnesium, zinc |
| Liver | Monthly | A, B12, iron, copper, folate—nature's multivitamin |
| Oysters | Occasionally | Zinc (74 mg per serving!), B12, copper |
🚀 Getting Started: 4-Week Micronutrient Optimization Plan
Week 1: Assessment & Foundation
Tasks:
- Track your diet for 3 days using Cronometer (shows micronutrient intake)
- Note any symptoms that might be micronutrient-related
- Identify your risk factors (diet pattern, age, medications, lifestyle)
- Order blood tests if warranted: Vitamin D, B12, ferritin (especially if at risk)
Daily additions:
- Start with eggs most mornings (choline, B12, D)
- Add leafy greens to one meal (K, folate, magnesium)
Week 2: The Big 3 (D, Mg, B12)
Focus on the most commonly deficient nutrients:
- Vitamin D: Start 2,000-4,000 IU D3 daily with fat (unless test shows you're already optimal)
- Magnesium: Add 200-300 mg glycinate before bed (most people are low)
- B12: If vegan, vegetarian, or 50+, add 1,000 mcg methylcobalamin
What to notice: Better sleep (Mg)? More energy? Improved mood?
Week 3: Minerals & Synergies
Add supporting nutrients:
- K2 MK-7: 100-200 mcg if taking D3 (directs calcium to bones)
- Zinc + Copper: If indicated (15-30 mg zinc + 1-2 mg copper)
- Iron: Only if ferritin test shows low (<30 ng/mL)
Food focus:
- Add fatty fish 2x this week (D, B12, omega-3s, selenium)
- Include pumpkin seeds or almonds daily (magnesium, zinc)
Week 4 & Beyond: Fine-Tuning
Review:
- Get test results back and adjust
- Notice which additions made the biggest difference
- Establish sustainable habits
Maintenance stack for most people:
Daily:
├── Vitamin D3 (2,000-4,000 IU) — unless levels optimal
├── Vitamin K2 MK-7 (100-200 mcg) — with D3
├── Magnesium glycinate (200-400 mg) — evening
└── Omega-3s (if not eating fatty fish 2x/week)
Add if applicable:
├── B12 (if vegan, 50+, or on PPIs)
├── Iron (only if tested low)
└── Zinc + copper (if vegetarian or symptomatic)
🔧 Troubleshooting: Common Micronutrient Problems
Problem 1: "I take supplements but don't feel better"
Possible issues:
- Wrong form: Magnesium oxide (4% absorbed), folic acid vs. methylfolate, cyanocobalamin vs. methylcobalamin
- Poor timing: Fat-soluble vitamins without food, iron with coffee
- Not addressing the root cause: The supplement isn't what you actually need
- Interactions: Taking competing nutrients together (calcium + iron)
Solutions:
- Switch to better-absorbed forms (glycinate, citrate, methyl-forms)
- Take fat-soluble vitamins with meals containing fat
- Get tested to know what you're actually deficient in
- Space competing supplements
Problem 2: "My doctor says everything is normal"
The "normal" vs. "optimal" gap:
| Marker | Lab "Normal" | Optimal |
|---|---|---|
| Vitamin D | 20-100 ng/mL | 40-60 ng/mL |
| B12 | 200-900 pg/mL | 500+ pg/mL |
| Ferritin | 12-150 ng/mL | 30-100 ng/mL |
| Magnesium | 1.7-2.2 mg/dL | Serum unreliable—use RBC Mg |
What to do:
- Ask for exact numbers, not just "normal"
- Research optimal ranges (often narrower than lab ranges)
- If symptomatic and low-normal, consider therapeutic trial
Problem 3: "I eat healthy but still seem deficient"
Reasons healthy eaters can be low:
- Soil depletion: Produce has 30-76% fewer minerals than 50 years ago
- Stress: Burns through magnesium and B vitamins
- Gut issues: Poor absorption despite good intake
- Limited sun: Vitamin D can't come from food alone for most people
- No fatty fish: Omega-3s and vitamin D gap
- Vegetarian: B12, iron, zinc need special attention
Solutions:
- Accept that supplementation isn't "cheating"—modern life may require it
- Focus on the most commonly deficient: D, magnesium, omega-3s
- Address gut health if absorption is the issue
Problem 4: "I'm overwhelmed—what's the minimum I should take?"
The essential 3 for most people:
- Vitamin D3 (2,000-4,000 IU) — ~$5-10/year. Deficiency is epidemic.
- Magnesium glycinate (200-400 mg) — ~$15/year. 50%+ are low.
- Omega-3s (1-2g EPA+DHA) — ~$50-100/year. Only if not eating fatty fish.
Add if applicable:
- B12 if vegan/50+/on PPIs
- Iron only if tested low
Everything else: Work on food first.
❓ Common Questions
Should I take a multivitamin?
Multivitamins are "nutritional insurance," but often poorly formulated — low doses, poor forms, unnecessary ingredients. Targeted supplementation (vitamin D, magnesium, omega-3s) is generally more effective. If you do take a multi, choose one from a reputable brand with absorbable forms.
Can I get too much of a vitamin or mineral?
Yes, particularly fat-soluble vitamins (A, D, E, K) and certain minerals (iron, selenium, zinc). Water-soluble vitamins are safer (excess excreted), but megadoses can still cause issues. Stay within recommended upper limits unless supervised.
Do I need more micronutrients if I exercise?
Yes, especially with high training volume. Athletes may need more B vitamins, magnesium, iron, zinc, and antioxidants. Increased calorie intake from whole foods usually covers this, but some benefit from targeted supplementation.
Are synthetic vitamins as good as natural ones?
For most vitamins, synthetic forms work equally well. Exceptions: natural vitamin E is better absorbed; methylfolate may be preferable to folic acid for some people. Natural food sources provide additional beneficial compounds supplements don't.
What affects how well I absorb micronutrients?
Gut health (damaged gut = poor absorption), age (absorption decreases), medications (many deplete nutrients), food combinations (enhancers vs. inhibitors), and the form of the nutrient (e.g., heme vs. non-heme iron).
✅ Quick Reference (click to expand)
Priority Nutrients to Monitor
- Vitamin D — Test and supplement if low
- Magnesium — Supplement if diet is inadequate or symptomatic
- Omega-3s (EPA/DHA) — Eat fatty fish or supplement
- B12 — Mandatory for vegans; consider if 50+
- Iron — Monitor if menstruating, vegetarian, or fatigued
Signs You May Be Deficient
| Symptom | Possible Deficiencies |
|---|---|
| Fatigue | Iron, B12, D, magnesium |
| Poor immunity | D, zinc, C, A |
| Muscle cramps | Magnesium, potassium, calcium |
| Skin issues | A, zinc, biotin, omega-3s |
| Mood issues | D, B vitamins, magnesium, omega-3s |
| Hair loss | Iron, zinc, biotin, D |
| Poor wound healing | Zinc, C, protein |
Supplement Forms Matter
| Nutrient | Better Forms | Avoid |
|---|---|---|
| Vitamin D | D3 (cholecalciferol) | D2 (less effective) |
| Magnesium | Glycinate, citrate, threonate | Oxide (poor absorption) |
| B12 | Methylcobalamin, adenosylcobalamin | Cyanocobalamin (less direct) |
| Folate | Methylfolate (5-MTHF) | Folic acid (for some people) |
| Iron | Ferrous bisglycinate | Ferrous sulfate (GI issues) |
| Zinc | Zinc picolinate, citrate | Zinc oxide |
💡 Key Takeaways
- Micronutrients don't provide calories but are essential for every bodily function
- Deficiencies are surprisingly common — especially D, magnesium, B12, and iron
- Food first — Whole foods provide nutrients in balanced, bioavailable forms
- Interactions matter — Some nutrients help each other; others compete
- Fat-soluble vitamins can accumulate — Don't mega-dose A, D, E, K without testing
- Water-soluble vitamins need regular intake — Body doesn't store them (except B12)
- Test key markers — Especially vitamin D, B12, iron/ferritin before supplementing
- Form matters for supplements — Methylated B vitamins, chelated minerals absorb better
- Individual needs vary — Age, diet, lifestyle, stress, and medications all affect requirements
📚 Sources (click to expand)
General Micronutrients:
- NIH Office of Dietary Supplements. Nutrient Fact Sheets.
ods.od.nih.gov
—
- Linus Pauling Institute. Micronutrient Information Center.
lpi.oregonstate.edu
—
Nutrient Interactions:
- Minich D. Vitamin-Mineral Interactions. Metagenics, 2020.
—
- PMC. Nutrient synergy: definition, evidence, and future directions. 2023.
PMC10600480
—
Deficiency Prevalence:
- CDC. Micronutrient Facts.
cdc.gov/nutrition
—
See the Sources Library for complete references.
Assessment Guidance:
- When users report nonspecific symptoms (fatigue, brain fog, mood issues, poor immunity), always consider micronutrient status as a potential factor
- Ask about diet patterns: Do they eat fatty fish? Leafy greens? Organ meats? Eggs? These reveal likely gaps.
- Ask about lifestyle: Sun exposure? Stress levels? Medications? These affect needs and absorption.
- Ask about restrictions: Vegan? Vegetarian? Food allergies? These create specific deficiency risks.
Priority by Population:
| User Type | First-Line Recommendations |
|---|---|
| General adult | D3, magnesium, omega-3s (if no fatty fish) |
| Vegan/Vegetarian | B12 (mandatory), D3, omega-3s (algae), iron, zinc |
| Women 18-50 | Iron (if menstruating), D3, folate, magnesium |
| Adults 50+ | B12, D3, calcium, magnesium |
| Athletes | Magnesium, D3, zinc, iron (if tested low) |
| High stress | Magnesium, B vitamins, D3, omega-3s |
| Gut issues | Address absorption first; consider B12, iron, fat-soluble vitamins |
Common Mistakes to Catch:
- Supplementing without testing — Especially iron (can be harmful if not deficient)
- Wrong forms — Magnesium oxide, folic acid in those who need methylfolate, cyanocobalamin
- Poor timing — Fat-soluble vitamins without fat; iron with coffee/tea; calcium with iron
- Ignoring interactions — High-dose single nutrients without cofactors (D without K2)
- Lab "normal" complacency — Low-normal vitamin D (25 ng/mL) or B12 (250 pg/mL) may still be suboptimal
- Over-supplementing — Mega-doses of fat-soluble vitamins or minerals without need
Example Coaching Scenarios:
Scenario 1: "I'm always tired and my doctor says everything's normal"
- Response: "Fatigue with 'normal' labs is often a micronutrient issue. What were your exact vitamin D and B12 numbers? Lab 'normal' ranges are wide—you could be at 25 ng/mL D (low-normal but not optimal) or 250 pg/mL B12 (technically normal but many feel better at 500+). Also, serum magnesium is rarely tested and isn't reliable anyway—most people are low. Let's look at your numbers and symptoms together."
Scenario 2: "Should I take a multivitamin?"
- Response: "Multivitamins are 'nutritional insurance' but often poorly formulated. Most use cheap forms (magnesium oxide, folic acid) in doses too low to correct real deficiencies. A better approach: target the specific nutrients most people are low in—vitamin D3, magnesium glycinate, and omega-3s if you don't eat fatty fish. These will make a bigger difference than a scattershot multivitamin."
Scenario 3: "I eat healthy but still feel deficient"
- Response: "This is common! Even perfect diets face challenges: soil depletion has reduced mineral content in produce by 30-76% since 1950, vitamin D can't realistically come from food alone, stress burns through magnesium faster than most diets replenish, and modern life limits sun exposure. Targeted supplementation isn't 'cheating'—it's adapting to modern realities. D3, magnesium, and omega-3s are the foundation most people benefit from regardless of diet quality."
Scenario 4: "I'm vegan and worried about deficiencies"
- Response: "Smart concern. B12 supplementation is non-negotiable—there's no reliable plant source, and deficiency causes irreversible nerve damage. Beyond that, focus on: vitamin D3 (or D2 if strict vegan), algae-based omega-3s (EPA/DHA, not just ALA from flax), iron (monitor ferritin—plant iron absorbs poorly), and zinc (also lower bioavailability from plants). Eating vitamin C with iron-rich foods helps absorption significantly."
Red Flags to Address:
- Taking high-dose iron without testing → Risk of iron overload
- Mega-dosing vitamin A → Risk of toxicity, bone loss
- Taking calcium without D and K2 → May not reach bones; possible arterial calcification
- B12 below 200 pg/mL → Needs immediate supplementation
- Vitamin D below 20 ng/mL with symptoms → Needs therapeutic dosing
🔗 Dive Deeper
Detailed Guides:
- Vitamins — Complete guide to all 13 vitamins + choline (fat-soluble A, D, E, K; water-soluble B vitamins and C; methylation and MTHFR)
- Minerals — Complete guide to all essential minerals (7 macrominerals including magnesium and calcium; 9+ trace minerals including iron and zinc; emerging research on boron and silicon)
Related Topics:
- Macronutrients — Protein, carbs, and fats
- Supplements — When food isn't enough
- Gut Health — Absorption starts here
- Digestion — How nutrients are absorbed